Matches in Nanopublications for { <http://rdf.disgenet.org/resource/nanopub/NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_assertion> ?p ?o ?g. }
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- NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_assertion type Assertion NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_head.
- NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_assertion description "[To test this possibility, we synthesized R-carvedilol and assessed its effect on Ca(2+) release and VT. Like racemic carvedilol, R-carvedilol directly reduces the open duration of the cardiac ryanodine receptor (RyR2), suppresses spontaneous Ca(2+) oscillations in human embryonic kidney (HEK) 293 cells, Ca(2+) waves in cardiomyocytes in intact hearts and stress-induced VT in mice harbouring a catecholaminergic polymorphic ventricular tachycardia (CPVT)-causing RyR2 mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_provenance.
- NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_assertion evidence source_evidence_literature NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_provenance.
- NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_assertion SIO_000772 26348911 NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_provenance.
- NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_assertion wasDerivedFrom befree-2016 NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_provenance.
- NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_assertion wasGeneratedBy ECO_0000203 NP1293798.RAUce5LyCWNX9S2XKE44L33xYAUaJZcZTzT-x0cingadc130_provenance.