Matches in Nanopublications for { <http://rdf.disgenet.org/resource/nanopub/NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_assertion> ?p ?o ?g. }
Showing items 1 to 6 of
6
with 100 items per page.
- NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_assertion type Assertion NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_head.
- NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_assertion description "[Here we present evidence that activation of a cAMP pathway correlates with multiple cellular changes in these cells: (1) increased expression of the transcription factor microphthalmia; (2) increased melanogenesis; (3) increased association of the cyclin-dependent kinase inhibitors (CDK-Is) p27(KIP1) and p16(INK4) with CDK2 and CDK4, respectively; (4) failure to phosphorylate the retinoblastoma protein (pRB); (5) decreased expression of E2F1, E2F2, and E2F4 proteins; (6) loss of E2F DNA-binding activity; and (7) phenotypic changes characteristic of senescent cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_provenance.
- NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_assertion evidence source_evidence_literature NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_provenance.
- NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_assertion SIO_000772 10585280 NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_provenance.
- NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_assertion wasDerivedFrom befree-2016 NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_provenance.
- NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_assertion wasGeneratedBy ECO_0000203 NP269056.RACAyBbzCe9aiqPB3y1jYJn6tO5VR2VG12cbAnaOxKKAc130_provenance.