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- NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_assertion type Assertion NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_head.
- NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_assertion description "[Our results show that i) aPC induced the secretion of several cytokines in Ovcar-3 cells; ii) 61% of patients exhibited a concentration of plasma sEPCR well above the baseline (normal plasma level, 100 � 28 ng/ml); iii) comparing immune cell phenotypes in patients having a normal level of sEPCR with those having a high level of sEPCR, it was found that sEPCR levels were correlated with high intensity of cells expressing CD45ra, CD3, CD8, CD25 and low intensity of cells expressing CD56 (NK cells), CD294 (TH2 cells), IL-2, IL-10, IL-17a (TH17 cells), IL-21 (TH21 cells) and CD29 markers (r ? 0.60); and iv) high levels of sEPCR correlate with high levels of plasma bioactive proteins such as insulin-like growth factor-2 (IGFII), IL-13r?, macrophage inflammatory protein (MIP1?) and matrix metalloproteinase-7 (MMP-7) that have already been proposed as biomarkers for ovarian cancer and particularly those with poor prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_provenance.
- NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_assertion evidence source_evidence_literature NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_provenance.
- NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_assertion SIO_000772 23877403 NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_provenance.
- NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_assertion wasDerivedFrom befree-20150227 NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_provenance.
- NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_assertion wasGeneratedBy ECO_0000203 NP517570.RAZT7sSYflCM9wTzPcaAwfyAZOBzpdOc59BlUH_Rm9q0s130_provenance.