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- assertion description "[PPAR-? overexpression in colonic epithelial cells promoted CAC tumorigenesis in mice and increased IL-6 expression and STAT3 phosphorylation, whereas concomitant 15-LOX-1 expression in colonic epithelial cells (15-LOX-1-PPAR-?-Gut mice) suppressed these effects: the number of tumors per mouse (mean ? sem) was 4.22 ? 0.68 in wild-type littermates, 6.67 ? 0.83 in PPAR-?-Gut mice (P = 0.026), and 2.25 ? 0.25 in 15-LOX-1-PPAR-?-Gut mice (P = 0.0006).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." provenance.
- assertion evidence source_evidence_literature provenance.
- assertion SIO_000772 25713055 provenance.
- assertion wasDerivedFrom BEFREE provenance.
- assertion wasGeneratedBy ECO_0000203 provenance.