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- NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_assertion type Assertion NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_head.
- NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_assertion description "[Based on analyses of human glioblastoma multiforme (GBM) cell lines, normal astrocytes and clinical specimens from grade II astrocytomas (n=41) and grade IV GBM (n=60), we conclude that the DDR machinery is constitutively activated in gliomas, as documented by phosphorylated histone H2AX (gammaH2AX), activation of the ATM-Chk2-p53 pathway, 53BP1 foci and other markers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_provenance.
- NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_assertion evidence source_evidence_literature NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_provenance.
- NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_assertion SIO_000772 20581868 NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_provenance.
- NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_assertion wasDerivedFrom befree-2016 NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_provenance.
- NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_assertion wasGeneratedBy ECO_0000203 NP821851.RA5_ncePwXoNPrgwu97BF1nhF738IrVHE959GbQkB7sE8130_provenance.