Matches in Nanopublications for { <http://rdf.disgenet.org/resource/nanopub/NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_assertion> ?p ?o ?g. }
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- NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_assertion type Assertion NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_head.
- NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_assertion description "[As to the mechanisms involved, we have found that Mfn2 loss-of-function represses nuclear-encoded subunits of OXPHOS complexes I, II, III and V, whereas Mfn2 overexpression induced the subunits of complexes I, IV and V. Obesity-induced Mfn2 deficiency in rat skeletal muscle was also associated with a decrease in the subunits of complexes I, II, III and V. In addition, the effect of Mfn2 overexpression on mitochondrial metabolism was mimicked by a truncated Mfn2 mutant that is inactive as a mitochondrial fusion protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_provenance.
- NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_assertion evidence source_evidence_literature NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_provenance.
- NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_assertion SIO_000772 15829499 NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_provenance.
- NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_assertion wasDerivedFrom befree-20150227 NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_provenance.
- NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_assertion wasGeneratedBy ECO_0000203 NP832483.RA9p_DqM97cLSiPFQxfKu2AeQR1hyB07ECqmT3mVTXdAM130_provenance.