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- NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_assertion type Assertion NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_head.
- NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_assertion description "[We found that long-term exposure to hypoxia a) significantly inhibited lung cancer tumor growth in xenograft and orthotopic models in rats, b) significantly reduced lymphatic metastasis of the lung cancer in rats and decreased lung metastasis of Lewis lung carcinoma in mice, c) reduced lung cancer cell proliferation and cell cycle progression in vitro, d) decreased growth of the tumors from hypoxia-pretreated A549 cells, e) decreased Na+-K+ ATPase ?1 expression in hypoxic lung cancer tumors, and f) increased expression of hypoxia inducible factors (HIF1? and HIF2?) but decreased microvessel density in the lung cancer tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_provenance.
- NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_assertion evidence source_evidence_literature NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_provenance.
- NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_assertion SIO_000772 21812995 NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_provenance.
- NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_assertion wasDerivedFrom befree-2016 NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_provenance.
- NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_assertion wasGeneratedBy ECO_0000203 NP914406.RAUE-Oq54hpTtKfU_1HObP6IxYQs39fUYxks29Jyz8gd8130_provenance.