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- _4 value "(D) Expression of spermatogenesis- and spermiogenesis-related genes in the testes of 12-week-old AF5q31+/+, AF5q31+/-, and AF5q31-/- male mice. RT-PCR for GAPDH confirms the equivalent amounts of RNAs used for the analysis. Furthermore, testis-specific cytoplasmic poly(A) polymerase (Tpap), sperm outer dense fiber protein (RT7), heat shock protein Hsc70t, mitochondria capsule selenoprotein (Mcs aka Smcp), and phosphoglycerate kinase-2 (Pgk2), which are known to be expressed in spermiogenesis, were not significantly changed, except for a slight decrease of Mcs in the mutant testes. Intriguingly, expression levels of TP2 (Tnp2), Prm1, and Prm2 were drastically decreased and that of TP1(Tnp1) was slightly decreased in AF5q31 -/- testes." provenance.
- _4 wasQuotedFrom 16024815 provenance.