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- _5 value "Electrophoretic mobility shift assays demonstrate that homeodomain transcription factors PDX1 and Nkx2.2 can bind to the sequence element located at -800 base pairs. .....When co-transfected into NIH3T3 cells, PDX-1 can activate the b-cell-specific enhancer linked to the rat prolactin promoter (Fig. 5B). Nkx2-2, however, cannot activate the mini-enhancer by itself or in combination with PDX-1 (Fig. 5B), although it can activate the intact nkx6.1 promoter" provenance.
- _5 wasQuotedFrom 10938085 provenance.