Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA0UaSylp9-qDuy-lAuE9l8o5bqA1uZoBUNQR3xuJhwFg#_5> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _5 value "OMIM summary: Human: Telethonin is a sarcomeric protein of 19 kD found exclusively in striated and cardiac muscle ({3:Valle et al., 1997}). It appears to be localized to the Z-disc of adult skeletal muscle and cultured myocytes. Telethonin is a substrate of titin (TTN; {188840}), which acts as a molecular 'ruler' for the assembly of the sarcomere by providing spatially defined binding sites for other sarcomeric proteins. After activation by phosphorylation and calcium/calmodulin binding, titin phosphorylates the C-terminal domain of telethonin in early differentiating myocytes." provenance.
- _5 wasQuotedFrom _4 provenance.