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- _6 value "Because PDK1 has been shown to phosphorylate p70S6 kinase directly [56], one might have assumed that activation of mTOR was dispensable in some settings of p70S6K activation. That might still be the case; alternatively, it might be that p70S6K must first be primed by another kinase, such as mTOR, before being activated by PDK1 [57,58]" provenance.
- _6 wasQuotedFrom 12928036 provenance.