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- _2 value "CYP4B1 is induced by peroxisomal proliferators such as the hypolipidemic drug and clofibric acid, and it can metabolize fatty acids at the omega-carbon (Zeldin et al., 1995). 12-hydroxy-5,8,11, 14-eicosatetraenoic acid (12(R)-HETE) and 12-hydroxy-5,8, 14-eicosatrienoic acid (12(R)-HETrE ). Both metabolites possess potent inflammatory properties, with 12(R)-HETrE being a powerful angiogenic factor, and they assume the role of inflammatory mediators" provenance.
- _2 wasQuotedFrom 10336559 provenance.