Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA0ztOs6XYSNVH8DYEMHgL9z7k2_2s2vKEwsCCzxRzEwc#_3> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _3 value "From our cDNA microarray experiments, we determined that a variety of nucleotide synthesis-related genes, including TS, were downregulated with lapatinib, and this was apparent in HER2-amplified cells (SNU216 gastric cancer cell line). Figure 2. Lapatinib downregulates fluoropyrimidine-target genes. The expressions of representative nucleotide synthesis-related genes [E2F-1, TS, TK1 (thymidine kinase 1), DHFR(dihydrofolate reductase), RRM2 (ribonucleotide reductase M2 polypeptide), DUT (DUTP pyrophosphatase), NME1 (nuclear diphosphate kinase 1)] were reduced as the result of gefitinib or lapatinib treatment in TKI-sensitive cells." provenance.
- _3 wasQuotedFrom 19529774 provenance.