Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA1akQvYDCVZqL-ufUxRnGI_SdzTMznE67cWb5CoSK9aI#_6> ?p ?o ?g. }
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- _6 value "On exposure of the cells to TGFbeta1, S100C/A11 was phosphorylated, bound to nucleolin, and transferred to the nucleus, resulting in induction of p21WAF1/CIP1 and p15INK4B through activation of Sp1. Protein kinase C alpha (PKCalpha) was shown to phosphorylate 10Thr of S100C/A11, which is a critical event for the signal transduction. The TGFbeta1-induced growth inhibition was almost completely mitigated when PKCalpha activity was blocked or when S100C/A11 was functionally sequestered." provenance.
- _6 wasQuotedFrom 15051732 provenance.