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- _4 value "To validate the influence of miR-221/222 cluster on the p27Kip1 target, we transfected the miR-221 and/or miR-222, or their inhibitors, as 20-O-Me-221 and/or 20-O-Me-222, into the TPC-1 thyroid papillary carcinoma cell line and HeLa cells, and we searched for changes in p27Kip1 protein levels by western blot analysis. Introduction of both miR-221 and miR-222 decreased p27Kip1 protein levels (Fig. 1B)." provenance.
- _4 wasQuotedFrom 17914108 provenance.