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{ <http://www.tkuhn.ch/bel2nanopub/RA1gDEKsCdH8RiymLs94lh8I18C-8cQRtLz75YefyQjYM#_5> ?p ?o ?g. }
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Phosphoylation of pRb and concomitant release of E2F repres200 sion is catalyzed by cyclin D-dependent kinases, cdk4 , in response to extracellular signals and by the cyclin E- and A-dependent kinase, cdk2.
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