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{ <http://www.tkuhn.ch/bel2nanopub/RA1pN5vJrd5FFekgM6hgWU7WCa710nItfYAM83tiJNAdo#_5> ?p ?o ?g. }
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ASK1 phosphorylates and activates MKK4/7, which then activates the c-Jun NH2-terminal protein kinases (JNKs), also known as the stress-activated protein kinases. JNK activation requires phosphorylation at a specific motif (TPY).
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