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- _5 value "FKHR, FKHRL1 and AFX are each phosphorylated by PKB at three residues in vitro, and, in co-transfection experiments with FKHR, these were shown to be Thr-24, Ser-256 and Ser-319 [9-14]. The half time for phosphorylation of each site was 2-5 min. In contrast, the mutation S256A completely prevented phosphorylation at Thr-24 and Ser-319 ... but the mutation T24A did not prevent phosphorylation at Ser-256 or Ser-319 ..., and the mutation S319A did not prevent the phosphorylation of Thr-24 and Ser-256..." provenance.
- _5 wasQuotedFrom 11237865 provenance.