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- _4 value "HNE (like oxidized LDLS) is also able to inhibit the proteasome activity and subsequent proteolysis of IkBa, possibly through a modification of proteasome proteins by 4-HNE.[72,73] Finally, both mechanisms may converge to inhibit NF-kB activation and subsequent expression of adhesion molecules, such as ICAM-1, VCAM-1 and E-selectin, in human aortic endothelial cells.[74]" provenance.
- _4 wasQuotedFrom 15346645 provenance.