Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA3M4J4zn2hanHiiu3hvKAgcQ3VgOhqN6p6lhPppobh0k#_4> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _4 value "We found that a fragment of the IL-6 promoter containing the site specifically binds highly purified NF-KB protein and the NF-KB protein in nuclear extracts of phorbol ester-induced Jurkat cells. Mutations of the NF-KB site abolished complex formation with both purified NF-KB and the nuclear extract protein. Transient expression of chloramphenicol acetyltransferase (CAT) plasmids containing the IL-6 promoter revealed very little activity of the promoter in U-937 monocytic cells and in HeLa cells before stimulation. However, stimulation of U-937 and HeLa cells by inducers of NF-KB led to a dramatic increase in CAT activity." provenance.
- _4 wasQuotedFrom 2183031 provenance.