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- _4 value "Plating of serum-starved cells expressing ephrin-A5 on fibronectin induced phosphorylation of Mapk3. Similarly plating of cells on EphA5-Fc resulted in the phosphorylation of Mapk3, but the activation appeared more robust and prolonged. Preincubation of the cells with a function-blocking antibody specific for beta1 integrin before plating on EphA5-Fc slightly reduced the level of the phosphorylation. These results suggested that only a part of the Mapk3 activation seen in response to ephrin-A5 engagement was due to signalling cascade downstream of integrin beta1." provenance.
- _4 wasQuotedFrom 11032807 provenance.