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- _3 value "acidification or glucocorticoids increase the maximal activity and subunit mRNA levels of branched chain alpha-ketoacid dehydrogenase [BCKAD] in various cell types dexamethasone concurrently stimulated E2 subunit promoter activity and reduced the binding of nuclear factor-kappaB to a site in the E2 promoter thus acidification and glucocorticoids independently enhance BCKAD subunit gene expression, and the glucocorticoid repsonse in the E2 subunit involves interference with NF-kappaB, which may act as a transrepressor" provenance.
- _3 wasQuotedFrom 11287331 provenance.