Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA58Mjuh0UZdV6dRQvKLI5Jwr8FHpJQEFW3eQEiK071SI#_7> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _7 value "We now show that the regulation of E2F1 by TopBP1 involves the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway, and is independent of pocket proteins. Akt phosphorylates TopBP1 in vitro and in vivo.... The Akt-dependent oligomerization is crucial for TopBP1 to interact with and repress E2F1." provenance.
- _7 wasQuotedFrom 17006541 provenance.