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- _2 value "The lpr gene has been identified as a defect in the Fas gene, which encodes a lymphocyte surface protein associated with apoptosis and shares homology with the tumor necrosis factor-alpha receptor. This finding is important as it may quickly lead to identification of the gld gene product, which is thought to be a ligand for Fas. Also, it clearly identifies autoimmune disease as originating from a defect in the ability to induce cell death in lymphocytes." provenance.
- _2 wasQuotedFrom 1419495 provenance.