Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA5_OpfzUuoJHGlVsMPhnlIO8E2k-iKr0qfpXYLWP5EIY#_4> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _4 value "identified miR-221 and miR-222 (miR-221&222) as potent regulators of p27(Kip1), a cell cycle inhibitor and tumor suppressor. Using miRNA inhibitors, we demonstrate that certain cancer cell lines require high activity of miR-221&222 to maintain low p27(Kip1) levels and continuous proliferation. Interestingly, high levels of miR-221&222 appear in glioblastomas and correlate with low levels of p27(Kip1) protein. " provenance.
- _4 wasQuotedFrom 17627278 provenance.