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- _5 value "Hdac inhibitors disrupt Oct1 binding to the octamer element Oct1 interacts with the H2A octamer element with a high efficiency and represses Ifng-inducible H2A promtoer activation in Rb-defective tumor cell lines the reduction in binding activity seen for Oct1 was specific, as 2 other proteins, Nfy and Yy1, were not affected in their ability to bind DNA following treatment of the cells with Hdac inhibitors" provenance.
- _5 wasQuotedFrom 11533238 provenance.