Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RA6l8znIgh3Y2n59CWZckaUAOn4L0LKqrFmoO6XL5k_AA#_7> ?p ?o ?g. }
Showing items 1 to 2 of
2
with 100 items per page.
- _7 value "Transcriptional activation involves alterations in chromatin structure mediated by ATP-dependent chromatin-remodeling enzymes in conjunction with factors that contain histone acetyltransferase (HAT) activity [17]. Consistent with this concept is the observation that ER recruits BRG1, a mammalian homologue of a component of the SWI/SNF chromatin remodeling complex, to EREs in a cooperative manner with HATs [18]. Further, many ER coactivators possess intrinsic HAT activities, including CBP/p300, p/CAF, and TAFII250 [19-21]. Other coactivators such as the p160 coactivators facilitate ER transcription by serving as platforms to recruit HATs and protein methyltransferases." provenance.
- _7 wasQuotedFrom 14680484 provenance.