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- _4 value "Akt has been suggested to be important in transmission of the insulin signal, by phosphorylation of the enzyme GSK-3 (see below), the forkhead transcription factors and cAMP response element-binding protein38,39 Other AGC kinases that are downstream of PI(3)K include serum- and glucocorticoid- regulated kinase and the atypical PKCs, PKC-z and -l42. Akt and/or the atypical PKCs seem to be required for insulinstimulated glucose transport." provenance.
- _4 wasQuotedFrom 11742412 provenance.