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- _3 value "To this end, we employed 1) PD 98059 and U0126 (2 h and 15 min of incubation, respectively), which inhibit MEK (MAPKK); and 2) a dominant-negative MEK variant that inhibits cellular MEK (see \"Materials and Methods\"). The results, shown in Fig. 3, A-C, demonstrate that induction of Ha-Ras by H2O2 was abolished by MEK inhibition. " provenance.
- _3 wasQuotedFrom 16081426 provenance.