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- _3 value "Stromal vascular cultures containing newly differentiated human adipocytes were pretreated with a vehicle (dimethyl sulfoxide) for 1 hour, then with 1 microM BRL49653 (PPARgamma agonist) for 24hours and subsequently treated with 30microM trans-10, cis-12 conjugated linoleic acid for an additional 24hours. CLA treatment conferred the ability of ERK1/2 to phosphorylate its nuclear substrate ELK1 in vitro. Pretreatment with BRL49653 blocked the CLA mediated ability of ERK1/2 to phosphorylate ELK-1" provenance.
- _3 wasQuotedFrom 15067015 provenance.