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- _8 value "Contrary to the corepressors, the p160 NR coactivators bind to liganded NRs to mediate transcriptional activation through recruitment of histone acetyltransferases (10). The p160 coactivators include SRC-1 (11), GRIP1/TIF2 (12-14), and RAC3/ACTR/AIB1/pCIP/TRAM-1 (15-19). These coactivators also interact with histone acetyltransferases such as CREB-binding protein/p300 and P/CAF (22,23), tethering histone acetyltransferase activity to target promoters." provenance.
- _8 wasQuotedFrom 15184363 provenance.