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- _3 value "Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity.Electrophoretic mobility shift and reporter assays showed that ceramide reduced the DNA binding activity and transactivation capability of thyroid transcription factor 1 (TTF-1/Nkx2.1), a key factor for SP-B promoter activity. " provenance.
- _3 wasQuotedFrom 16183668 provenance.