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- _5 value "In the p53-dependent pathway, p53 accumulates following E2F1 expression [29] through activation of the cyclin-dependent kinase inhibitor 2A (CDKN2A) transcript p14ARF, which in turn interacts with mouse double minutes (MDM2), thereby preventing MDM2 from targeting p53 for ubiquitination and subsequent degradation" provenance.
- _5 wasQuotedFrom 16530485 provenance.