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- _3 value "The mRNA expression profile of GLUT-1, HK-2, and PFKFB3 genes whose transcriptional up-regulation under hypoxia is HIF-1a dependent (21, 32), was also determined (Fig. 2B). Consistent with the accumulation of HIF-1a, an increase in the expression level of the three mRNAs was observed in cells subjected to hypoxia and, as expected (33), only GLUT-1 mRNA was upregulated under glucose deprivation." provenance.
- _3 wasQuotedFrom 17638880 provenance.