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- _4 value "MMP-2 binds to ?v?3 at the cell surface, and blocking this binding inhibits MMP-2 protease activity in cultured cells, suppressing angiogenesis and tumour growth in chorioallantoic membrane assays43.Conversely, the membrane MMP (MT-1) cleaves ?v?3, enhancing the ligand binding activity of this integrin44. So,?v?3 seems to be important in regulating angiogenesis in adult animals." provenance.
- _4 wasQuotedFrom 12635171 provenance.