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- _5 value "Based on the Cot knock-out mouse data (17), it is believed that intact Cot kinase activity is required for the production of LPS-induced production of inflammatory cytokines such as TNF- and IL-1 and other inflammatory mediators, such as prostaglandin E2, produced by cyclooxygenase-2 (COX-2) Cot knock-out mouse in which Cot mediates LPS-induced TNF- and IL-1 production in monocytes and macrophages" provenance.
- _5 wasQuotedFrom 12975377 provenance.