Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RABqTKjyYd9iqcsDcuKd4yzDmkmuk-O2TDHbTTSb0x0KY#_6> ?p ?o ?g. }
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- _6 value "We show here that PGC-1, a cold-inducible coactivator of nuclear receptors, stimulates mitochondrial biogenesis and respiration in muscle cells through an induction of uncoupling protein 2 (UCP-2) and through regulation of the nuclear respiratory factors (NRFs). PGC-1 stimulates a powerful induction of NRF-1 and NRF-2 gene expression; in addition, PGC-1 binds to and coactivates the transcriptional function of NRF-1 on the promoter for mitochondrial transcription factor A (mtTFA)" provenance.
- _6 wasQuotedFrom 10412986 provenance.