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{ <http://www.tkuhn.ch/bel2nanopub/RAC59RTo5csnkVwI0udqlxdqwbDrRaGVyme7tjzwfEuSc#_5> ?p ?o ?g. }
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Activation of IKK depends on phosphorylation; serines 177 and 181 in the activation loop of IKKbeta (176 and 180 in IKKalpha?) are the specific sites whose phosphorylation causes conformational changes resulting in kinase activation .
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