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- _7 value "An analysis using a phosphotyrosine-specific antibody revealed that in T47D/puro cells, two of the three Shc isoforms, p46shc and p52shc, became highly phosphorylated in response to EGF and NDF. In the T47D/5R cells, the NDFinduced tyrosine phosphorylation of both proteins was reduced by 90% (Fig. 7A). EGF-induced Shc phosphorylation was also reduced in these cells, albeit to a lesser extent (63 and 41% for p46shc and p52shc, respectively)." provenance.
- _7 wasQuotedFrom 7532277 provenance.