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- _6 value "Gene expression microarray analysis under various induction conditions identified other T113242-activated genes affected by a decrease in MIZ-1 and inhibition of the ERK pathway. there are a number of genes that display the same pattern of sensitivity to T113242 and PD98059 as LDLR: gene products in this list include apoptosis regulators (LAGLS1, MCL1, IER3, BCL2L1, GG2-1), signal transducers (INPP1, EPHA2, LIF, IGFBP1, ACTN1, GPR126, GPRC5C, SFN), transcription factors (SOX4, ZFP36L1, MAFF), cytoskeleton-associated proteins (SPTBN1, KRT18, VASP, ARPC2, TUBA3), cell cycle regulators (TIMP1, CKS2, AREG, CDKN1B, BTG3), cell adhesion proteins (LAMB1, ITGAN, ICAM1, IL-8, MCAM, FN1), and metabolic proteins (OSBPL10, FACL5, KYNU, GK, GOT1, ARG2)." provenance.
- _6 wasQuotedFrom 14704274 provenance.