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{ <http://www.tkuhn.ch/bel2nanopub/RADxgjTNKWBUOOl3CNUaWCDWtsPBtIZXIny4raUloceiM#_6> ?p ?o ?g. }
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5LO stabilizes p53 through phosphorylation at Ser15 and increases expression of the p53-transcriptional target p21. This is achieved by regulating ROS production. Indeed, ROS are increased in 5LO-arrested cells
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_6
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