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- _4 value "# GeneRif: When expressed in respiratory epithelial cells and cell lines, protease-activated receptor 1 (PAR1)induces the release of IL-6, IL-8, and PGE2. Agonist peptides corresponding to the nascent N termini of PAR-1, PAR-2, and PAR-4 induced the release of cytokines from A549, BEAS-2B, and HBECs with a rank order of potency of PAR-2 > PAR-4 > PAR-1 at 400 microM. PAR-1, PAR-2, and PAR-4 also caused the release of PGE(2) from A549 and HBECs." provenance.
- _4 wasQuotedFrom 11907122 provenance.