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- _6 value "In hypoxia, VEGF transcription is upregulated by HIF18, 19, mRNA stability is increased by binding of proteins to specific sequences in the 3' UTR71, and an internal ribosomal entry site allows preserved translation in the face of normal cellular hypoxic shutdown72. The biological activity of secreted VEGF is further influenced by hypoxia-inducible expression of the Flt-1 receptor49," provenance.
- _6 wasQuotedFrom 12778166 provenance.