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- _5 value "beta-catenin, which then binds T cell factor-4 (Tcf-4), causing increased transcriptional activation of unknown genes. Here, the c-MYC oncogene is identified as a target gene in this signaling pathway. Expression of c-MYC was shown to be activated by beta-catenin, and these effects were mediated through Tcf-4 binding sites in the c-MYC promoter" provenance.
- _5 wasQuotedFrom 9727977 provenance.