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- _5 value "Since DCs are one of the primary cells that respond to danger signals [10, 38] , we assessed their activation status by examining the cell surface expression of MHCII and the costimulatory markers CD86 (B7.2) and CD40. In Tlr4 WT animals, the expression of MHCII, CD86 and CD40 on BAL DCs increased upon subacute CS exposure compared to air exposure ( fig. 4 a).In the subacute experiment, the MHCII, CD86 and CD40 expression levels on BAL DCs in CS-exposed Tlr4 defective mice were significantly lower than in CS-exposed Tlr4 WT mice (p ! 0.001) ( fig. 4 a)." provenance.
- _5 wasQuotedFrom 16940747 provenance.