Matches in Nanopublications for { <http://www.tkuhn.ch/bel2nanopub/RAI5m4XITNpz0jld-XPY0mPLo6gG2clnunw5slzqwGnpM#_6> ?p ?o ?g. }
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- _6 value "Since genes encoding ecto-5'-nucleotidase (eN) and adenosine deaminase (ADA) contain TCF/LEF consensus binding sites, we asked whether Wnt/beta-catenin signaling, a pathway that is deregulated in several human tumors, targets the expression of these genes and thus influence extracellular adenosine generation. Our results show that beta-catenin strongly increased the activity of the 969-bp promoter of eN and this increase depended on the presence of TCF-1 transcription factor." provenance.
- _6 wasQuotedFrom 15149841 provenance.