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- _4 value "re hyperosmotic stress This element includes the same Sp1 DNA binding site found for FSH regulation of the SGK promoter, and the hyperosmotic stress stimulation of SGK transcription requires the stimulus-regulated binding of the Sp1 transcription factor to this site (filled box labeled Sp1 in figure 2). Sorbitol activates the SGK hyperosmotic stress regulated element as a downstream target of the MKK3 MKK6-p38 MAPK stress signaling cascade" provenance.
- _4 wasQuotedFrom 12649597 provenance.