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- _3 value "Exposure to thrombin induced a redistribution of VE-cadherin into a zigzag wide pattern typical for unstable and activated junctions and the generation of intercellular gaps. Ang-1 preincubation attenuated the effect of thrombin on VE-cadherin redistribution and gap formation. However, still some intercellular gaps were visible in accordance with the thrombin-induced permeability in Ang-1 treated cells (Figure 3c). In contrast, the effect of thrombin was enhanced in Ang-2 treated cells, which resulted in even wider VE-cadherin staining and a stronger zigzag pattern together with more intercellular gaps (Figure 3c). " provenance.
- _3 wasQuotedFrom 21858121 provenance.