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- _5 value "The T638 phosphorylation site is not required for the catalytic function of PKCalpha per se, but serves to control the duration of activation by regulating the rate of dephosphorylation and inactivation of the protein. This is achieved through the cooperative interaction between the T638 and T497 sites; if either of these residues is not phosphorylated, the protein is supersensitive to phosphatase action." provenance.
- _5 wasQuotedFrom 8805373 provenance.