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- _4 value "We next assessed whether selective agonists would activate lung fibroblast PPAR-g. IMR-90 cells were transfected with a PPAR-dependent reporter construct, pFATP-luc, or control vector. Neither Tro nor Cig activated cells transfected with the control vector (data not shown), whereas Tro and Cig activated transcription of the PPAR reporter construct in a dose-dependent manner, with higher levels of activation demonstrated with Tro (Fig. 2). Thus specific agonists can activate PPAR-g expressed in human lung fibroblasts (IMR-90)." provenance.
- _4 wasQuotedFrom 18162602 provenance.